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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Non-Standardized Food Allergenic Extract [EPC]
3500 Mw) is a non-standardized food allergenic extract used in the diagnosis and treatment of specific IgE-mediated allergic sensitivities. It belongs to the class of non-standardized plant and food allergenic extracts.
Name
3500 Mw)
Raw Name
3500 MW)
Category
Non-Standardized Food Allergenic Extract [EPC]
Drug Count
3
Variant Count
3
Last Verified
February 17, 2026
About 3500 Mw)
3500 Mw) is a non-standardized food allergenic extract used in the diagnosis and treatment of specific IgE-mediated allergic sensitivities. It belongs to the class of non-standardized plant and food allergenic extracts.
Detailed information about 3500 Mw)
References used for this content
This page is for informational purposes only and does not replace medical advice. Consult a qualified healthcare professional before using any medication containing 3500 Mw).
This agent belongs to a broad class of drugs known as allergenic extracts. These products are regulated by the FDA's Center for Biologics Evaluation and Research (CBER) as biological products. 3500 Mw) is primarily utilized by allergists and immunologists to identify specific triggers in patients suffering from Type I hypersensitivity (immediate-type) allergies. The FDA approval history for allergenic extracts dates back several decades, with non-standardized extracts being maintained under strict manufacturing protocols to ensure consistency, despite the lack of a universal potency standard across different manufacturers.
The mechanism of action for 3500 Mw) is centered on the human immune system's recognition of specific proteins (antigens). When used for diagnostic purposes, such as a skin prick test, the extract is introduced into the epidermal layer of the skin. If the patient has pre-existing IgE (Immunoglobulin E) antibodies specific to the proteins in 3500 Mw), these antibodies—which are bound to the surface of mast cells and basophils—will recognize the allergen.
Upon recognition, the IgE molecules cross-link, triggering a process called degranulation. This results in the rapid release of inflammatory mediators, most notably histamine, leukotrienes, and prostaglandins. These chemicals cause local vasodilation (widening of blood vessels) and increased capillary permeability, which manifests clinically as a 'wheal' (a raised, itchy bump) and 'flare' (redness surrounding the bump). This localized reaction confirms the patient's sensitivity to the allergen.
When used in immunotherapy (allergy shots), the mechanism shifts toward inducing immune tolerance. Repeated, escalating doses of 3500 Mw) are injected subcutaneously. Over time, this process encourages the immune system to shift from a Th2-dominated response (which produces IgE) to a Th1-dominated response. It also promotes the production of IgG4 (blocking antibodies) and the expansion of regulatory T-cells (Tregs), which suppress the allergic cascade upon future exposure to the natural allergen.
Unlike traditional small-molecule drugs, the pharmacokinetics of biological extracts like 3500 Mw) are not characterized by traditional absorption, distribution, metabolism, and excretion (ADME) studies.
3500 Mw) is indicated for two primary clinical purposes:
3500 Mw) is typically supplied in the following forms:
> Important: Only your healthcare provider can determine if 3500 Mw) is right for your specific condition. The use of allergenic extracts requires specialized training and the availability of emergency equipment to treat potential anaphylaxis.
Dosage for 3500 Mw) is highly individualized and must be determined by an allergy specialist through careful titration. There is no 'standard' dose that applies to all patients.
3500 Mw) may be used in children, but the safety and efficacy depend on the child's age and the severity of their allergies.
No specific dosage adjustments are required for patients with renal impairment, as the proteins are naturally degraded by proteases. However, the patient's overall health must be stable before administration.
No dosage adjustments are necessary for hepatic impairment. The clearance of allergenic extracts does not involve hepatic CYP450 metabolism.
Caution is advised in elderly patients, particularly those with underlying cardiovascular disease. The risk of a systemic reaction may be more difficult to manage in patients with reduced cardiac reserve.
3500 Mw) is never self-administered. It must be administered by a healthcare professional in a clinical setting equipped with emergency resuscitation equipment, including epinephrine, oxygen, and intravenous fluids.
In immunotherapy, if a dose is missed, the next dose may need to be reduced depending on how much time has elapsed.
An overdose of 3500 Mw) occurs if too much extract is injected or if the concentration is increased too rapidly. This can lead to a severe systemic reaction or anaphylaxis.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose or skip appointments without medical guidance.
Most patients receiving 3500 Mw) will experience some form of local reaction. These are generally not dangerous but indicate the body's sensitivity to the extract.
> Warning: Stop taking 3500 Mw) and call your doctor immediately if you experience any of these symptoms of a systemic reaction.
When used correctly for immunotherapy, 3500 Mw) is intended to have a positive long-term effect by reducing allergic sensitivity. However, some patients may experience:
While 3500 Mw) may not have a specific individual black box warning for the '3500 Mw' fraction, the entire class of allergenic extracts carries a general warning regarding Anaphylaxis.
Report any unusual symptoms to your healthcare provider, even if they occur several hours after your appointment.
3500 Mw) is a potent biological agent. Its use is restricted to diagnostic and therapeutic protocols under the direct supervision of a physician. It is not for home use. Patients must be in a stable state of health before receiving an injection. If you are feeling ill, have a fever, or are experiencing an asthma flare-up, you must inform your doctor, as your injection may need to be postponed.
No specific FDA black box warning is uniquely assigned to the name '3500 Mw)', but as a Non-Standardized Food Allergenic Extract, it falls under the class-wide warning for all allergenic extracts. This warning emphasizes that severe systemic reactions, including anaphylaxis, can occur. The risk is highest during the build-up phase of immunotherapy and in patients with poorly controlled asthma. Administration must occur in a facility where emergency medications and equipment are immediately available.
3500 Mw) does not typically cause sedation. However, if a patient experiences a mild systemic reaction or receives antihistamines to treat a local reaction, they may feel drowsy. Patients should ensure they feel completely normal before driving after an appointment.
There is no direct chemical interaction between 3500 Mw) and alcohol. However, alcohol consumption can cause vasodilation and may theoretically increase the rate of absorption of the extract or mask the early symptoms of an allergic reaction. It is generally advised to avoid alcohol for several hours before and after an injection.
Immunotherapy with 3500 Mw) is a long-term commitment, often lasting 3 to 5 years. Stopping the treatment prematurely will likely result in the return of allergy symptoms. There is no 'withdrawal syndrome,' but the protective 'blocking antibodies' will gradually decrease over time if treatment is stopped.
> Important: Discuss all your medical conditions, especially respiratory or heart problems, with your healthcare provider before starting 3500 Mw).
For each interaction, the management strategy usually involves either temporary discontinuation of the interacting drug (for antihistamines) or a careful risk-benefit analysis by the physician (for beta-blockers).
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking, including over-the-counter allergy meds.
3500 Mw) must NEVER be used in the following circumstances:
These conditions require a careful risk-benefit analysis by the specialist:
Patients allergic to one food or plant in a specific family may show cross-sensitivity to 3500 Mw). For example, if 3500 Mw) is derived from a legume, patients with peanut allergies may react more strongly. Your doctor will review your history for related allergens.
> Important: Your healthcare provider will evaluate your complete medical history before prescribing 3500 Mw).
3500 Mw) is classified as FDA Pregnancy Category C. This means animal reproduction studies have not been conducted, and it is not known if it can cause fetal harm.
It is not known whether the components of 3500 Mw) are excreted in human milk. However, because these are large proteins that are likely digested in the infant's gut, the risk to a nursing infant is considered very low. The benefit of the mother's allergy control usually outweighs the theoretical risk.
3500 Mw) is used in children, but with caution.
Elderly patients (over 65) may have a higher prevalence of cardiovascular disease or may be taking medications like beta-blockers or ACE inhibitors. This makes the management of a systemic reaction more complex. Dosing should be cautious, and the physician must ensure the patient's heart health is adequate for immunotherapy.
Renal impairment does not significantly alter the clearance of 3500 Mw), as the proteins are broken down by proteases. No specific dose adjustments are required based on GFR, but overall clinical stability is required.
No adjustments are needed for patients with liver disease. The metabolic pathway for allergenic extracts does not involve the liver's detoxification enzymes.
> Important: Special populations require individualized medical assessment and may require more frequent monitoring during the build-up phase.
3500 Mw) acts as a specific antigen that interacts with the adaptive immune system. At the molecular level, the proteins in the extract bind to the Fab portion of antigen-specific IgE antibodies. These IgE antibodies are 'loaded' onto high-affinity FcεRI receptors on the surface of mast cells and basophils.
When the 3500 Mw) proteins cross-link two adjacent IgE molecules, a signal is sent to the interior of the mast cell, leading to an influx of calcium and the release of pre-formed mediators (histamine) and newly synthesized mediators (leukotrienes). In immunotherapy, the mechanism involves the induction of 'blocking' IgG4 antibodies and the modulation of T-cell responses (Th2 to Th1 shift).
| Parameter | Value |
|---|---|
| Bioavailability | Low (Skin Prick); Moderate (Subcutaneous) |
| Protein Binding | N/A (Interacts with IgE/IgG) |
| Half-life | Varies by protein component (hours to days) |
| Tmax | 15-20 minutes (Diagnostic) |
| Metabolism | Proteolysis by ubiquitous proteases |
| Excretion | Renal (as small peptides/amino acids) |
3500 Mw) is a member of the Non-Standardized Food Allergenic Extract [EPC] class. It is related to other allergenic extracts such as standardized grass pollens and dust mite extracts, but differs in that its potency is not measured against a national standard reference.
Common questions about 3500 Mw)
3500 Mw) is a non-standardized food allergenic extract used primarily for the diagnosis and treatment of specific allergies. In a diagnostic setting, it is applied during a skin prick test to see if a patient develops a wheal and flare reaction, indicating an allergy. In a therapeutic setting, it is used in allergen immunotherapy, also known as allergy shots. This involves giving gradually increasing doses of the extract to help the patient's immune system become less sensitive to the allergen over time. It is particularly useful for patients whose symptoms are not well-controlled by standard medications like antihistamines.
The most common side effects of 3500 Mw) are localized to the site where the extract was applied or injected. During skin testing, patients almost always experience an itchy, red bump called a wheal, which is the intended sign of a positive test. For those receiving immunotherapy injections, common side effects include redness, itching, and swelling at the injection site that can last for a day or two. Some patients may also experience mild hay fever-like symptoms, such as sneezing or a runny nose, shortly after the injection. These local reactions are usually manageable and do not indicate a dangerous situation unless they become very large.
It is generally recommended to avoid alcohol on the days you receive a 3500 Mw) injection or undergo skin testing. Alcohol can cause your blood vessels to dilate (expand), which might increase the speed at which the allergen is absorbed into your system, potentially increasing the risk of a systemic reaction. Furthermore, alcohol can sometimes mask the early warning signs of an allergic reaction, such as flushing or a rapid heartbeat. To ensure maximum safety and to allow your doctor to accurately monitor your response to the extract, it is best to abstain from alcohol for at least 24 hours around your appointment. Always discuss your lifestyle habits with your allergist.
The safety of 3500 Mw) during pregnancy is a complex issue that requires a consultation with an allergy specialist. It is classified as Pregnancy Category C, meaning there is limited data on its effects on human pregnancy. Most allergists will not start a new course of immunotherapy (the build-up phase) during pregnancy because the risk of a systemic reaction is highest at this time, and such a reaction could deprive the fetus of oxygen. However, if a patient is already on a stable maintenance dose and is tolerating the injections well, many doctors will continue the treatment throughout pregnancy. The goal is to avoid any changes that could trigger a severe allergic response.
The time it takes for 3500 Mw) to work depends on whether it is being used for testing or treatment. For diagnostic skin testing, the results are almost immediate, usually appearing within 15 to 20 minutes of the skin prick. For immunotherapy (allergy shots), the process is much slower. Most patients begin to notice a reduction in their allergy symptoms during the first year of treatment, typically after they have reached the maintenance dose. However, the full benefits of immunotherapy often take 2 to 3 years of consistent injections to achieve. It is a long-term treatment designed to change the way your immune system reacts to triggers.
Yes, you can stop taking 3500 Mw) injections suddenly without experiencing a 'withdrawal' in the traditional sense, as it is not an addictive medication. However, stopping the treatment before the recommended 3 to 5-year course is finished will likely result in the return of your allergy symptoms over time. The 'blocking antibodies' that your body builds up during immunotherapy will gradually fade if they are not maintained. If you need to stop treatment due to side effects or life changes, you should discuss a plan with your doctor. If you miss only a few doses, your doctor may simply need to adjust your next dose downward rather than stopping the treatment entirely.
If you miss a scheduled immunotherapy dose of 3500 Mw), you should contact your allergist's office as soon as possible to reschedule. Do not attempt to 'double up' on your next dose. Because the safety of immunotherapy depends on a very specific schedule of increasing doses, a missed appointment may require your doctor to repeat your last dose or even reduce the dose for your next visit. This is done to prevent a systemic reaction that could occur if too much time passes between injections. The longer the gap between doses, the more cautious your doctor will need to be when restarting your schedule.
There is no clinical evidence to suggest that 3500 Mw) or other allergenic extracts cause weight gain. These products consist of natural proteins and glycerin, which are administered in very small quantities that do not affect the body's metabolism or appetite. If you experience weight gain while undergoing allergy treatment, it is likely due to other factors, such as the use of oral corticosteroids (which are sometimes prescribed for severe allergies) or unrelated lifestyle changes. If you have concerns about your weight, you should discuss them with your primary care physician to identify the underlying cause.
3500 Mw) can be taken with many other medications, but there are some critical exceptions. You must inform your doctor if you are taking beta-blockers (often used for blood pressure or heart issues), as these can make it very difficult to treat a severe allergic reaction if one occurs. Additionally, you will need to stop taking antihistamines for several days before a skin test, as they will block the reaction and lead to a false negative result. Other medications like ACE inhibitors or MAOIs may also require special consideration. Always provide your allergist with a complete and updated list of all medications, including supplements, that you are currently taking.
The concept of 'generic' drugs works differently for biological products like 3500 Mw). Because allergenic extracts are complex mixtures derived from natural sources, they are not identical between different manufacturers. While multiple companies may produce a 'Non-Standardized Food Allergenic Extract,' they are considered 'comparable' rather than 'generic' in the way a chemical drug like ibuprofen is. If your doctor starts your treatment using a specific manufacturer's extract, they will generally prefer to keep you on that same brand to ensure consistency in your dosing. Switching between different manufacturers' extracts may require a temporary reduction in dose for safety.