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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Other
Acer Rubrum Whole, commonly known as Red Maple, is a biological substance primarily utilized as an allergenic extract for the diagnosis and treatment of pollen-induced allergic rhinitis and asthma. It belongs to the pharmacological class of allergenic extracts.
Name
Acer Rubrum Whole
Raw Name
ACER RUBRUM WHOLE
Category
Other
Drug Count
4
Variant Count
4
Last Verified
February 17, 2026
About Acer Rubrum Whole
Acer Rubrum Whole, commonly known as Red Maple, is a biological substance primarily utilized as an allergenic extract for the diagnosis and treatment of pollen-induced allergic rhinitis and asthma. It belongs to the pharmacological class of allergenic extracts.
Detailed information about Acer Rubrum Whole
This page is for informational purposes only and does not replace medical advice. Consult a qualified healthcare professional before using any medication containing Acer Rubrum Whole.
Acer Rubrum Whole, derived from the Red Maple tree, is a complex biological preparation classified by the U.S. Food and Drug Administration (FDA) as an allergenic extract. It is primarily used in clinical immunology for the purpose of allergen immunotherapy (AIT), also known as desensitization or 'allergy shots.' Acer Rubrum Whole belongs to a class of drugs called allergenic extracts, which are unique because they are not traditional chemical syntheses but are biological products derived from environmental sources. These extracts contain the specific proteins and glycoproteins responsible for triggering Type I hypersensitivity reactions (allergic reactions) in sensitized individuals.
The FDA approval history for allergenic extracts like Acer Rubrum Whole dates back several decades, falling under the Public Health Service Act. Unlike modern small-molecule drugs, these extracts are standardized or non-standardized based on their biological potency, often measured in Allergy Units (AU) or Bioequivalent Allergy Units (BAU). In the case of Acer Rubrum, it is specifically indicated for patients who exhibit clinical symptoms of seasonal allergic rhinitis or allergic asthma upon exposure to maple pollen, confirmed by positive skin prick tests or elevated serum IgE levels.
At the molecular level, Acer Rubrum Whole works through a process known as immunomodulation. When a patient is allergic to Red Maple, their immune system incorrectly identifies the pollen proteins as harmful pathogens, leading to the production of Immunoglobulin E (IgE) antibodies. These IgE antibodies bind to mast cells and basophils. Upon subsequent exposure to the pollen, the allergen cross-links the IgE, triggering the release of inflammatory mediators like histamine, leukotrienes, and cytokines, which cause the classic symptoms of hay fever and asthma.
When administered as immunotherapy, Acer Rubrum Whole is introduced to the body in gradually increasing doses. This repetitive exposure shifts the immune response from a Th2-dominated profile (allergic) to a Th1-dominated profile. It induces the production of 'blocking antibodies,' specifically IgG4, which compete with IgE for allergen binding. Furthermore, it promotes the expansion of regulatory T cells (Tregs) that secrete IL-10 and TGF-beta, effectively suppressing the allergic cascade and inducing long-term clinical tolerance. This means the patient eventually stops reacting to environmental Red Maple pollen.
Acer Rubrum Whole is FDA-indicated for:
Off-label uses may include the treatment of oral allergy syndrome (OAS) where cross-reactivity between maple pollen and certain fruits occurs, though this should only be managed by a board-certified allergist.
> Important: Only your healthcare provider can determine if Acer Rubrum Whole is right for your specific condition. Immunotherapy must be initiated and monitored by a specialist trained in managing anaphylaxis.
Dosage for Acer Rubrum Whole is highly individualized and follows a 'Build-up Phase' and a 'Maintenance Phase.'
Acer Rubrum Whole is generally considered safe for children, typically those aged 5 years and older. Dosing schedules for pediatric patients are often identical to adult schedules, though the initial starting dose may be more conservative if the child is highly sensitive. It is not usually recommended for children under the age of 5 due to the difficulty of communicating systemic symptoms of a reaction.
No specific dosage adjustments are required for patients with kidney disease, as the proteins are not cleared via renal filtration. However, the patient's overall health must be stable.
No dosage adjustments are needed for liver impairment. The metabolism of allergenic extracts is independent of hepatic CYP450 pathways.
Caution is advised in elderly patients, particularly those with underlying cardiovascular disease. The risk-benefit ratio must be carefully weighed because the elderly may be less able to tolerate the hemodynamic stress of a systemic allergic reaction or the administration of epinephrine if a reaction occurs.
If a dose is missed during the build-up phase, the next dose may need to be reduced or repeated rather than increased. If a maintenance dose is missed by more than a week, the physician may reduce the dose temporarily to ensure safety. Never 'double up' on doses to catch up.
An overdose of Acer Rubrum Whole (either by volume or concentration) significantly increases the risk of a systemic reaction or anaphylaxis.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose without medical guidance. Always inform your doctor if you feel unwell on the day of your scheduled injection.
Local reactions are the most frequent side effects associated with Acer Rubrum Whole injections. These occur at the site of administration and are usually considered a sign that the immune system is responding to the extract.
These reactions are often referred to as 'Large Local Reactions' or mild systemic symptoms.
> Warning: Stop taking Acer Rubrum Whole and call your doctor or emergency services immediately if you experience any of these symptoms of anaphylaxis.
There are no known long-term 'toxic' effects of Acer Rubrum Whole, as it is a biological protein. However, long-term immunotherapy can lead to a permanent shift in the immune system. In rare cases, patients may develop 'Arthus-type' reactions (Type III hypersensitivity), which involve vasculitis or joint pain due to immune complex formation, though this is extremely uncommon with modern standardized extracts.
Report any unusual symptoms to your healthcare provider, especially if local reactions begin to increase in size significantly from one week to the next.
Acer Rubrum Whole is intended only for patients with a documented allergy to Red Maple pollen. It is not a general 'allergy medicine' and will not work for allergies to dust mites, pets, or other trees unless those are also included in the extract mix. Safety depends heavily on the '30-minute rule'—staying for observation after every dose.
No FDA black box warnings exist for Acer Rubrum Whole specifically as a chemical entity, but the entire class of injectable allergenic extracts carries a boxed warning regarding the risk of severe, life-threatening systemic reactions (anaphylaxis). The warning emphasizes that these products are not for home use and require strict clinical supervision.
Acer Rubrum Whole generally does not cause drowsiness. However, if a patient experiences a mild systemic reaction or receives epinephrine, they should not drive until they are fully recovered and cleared by a physician.
There is no direct interaction between alcohol and Acer Rubrum Whole. However, alcohol consumption can cause vasodilation, which may theoretically increase the rate of allergen absorption or mask the early symptoms of an allergic reaction. It is best to avoid alcohol for several hours after an injection.
Tapering is not required for Acer Rubrum Whole. However, if therapy is stopped for several weeks and then restarted, the doctor must significantly reduce the dose to avoid a reaction due to the loss of 'immunological priming.' Sudden discontinuation simply results in the gradual return of allergy symptoms over the following months.
> Important: Discuss all your medical conditions, especially heart or lung problems, with your healthcare provider before starting Acer Rubrum Whole.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking. A complete list is vital for your safety during immunotherapy.
Acer Rubrum Whole contains proteins that may cross-react with other members of the Acer genus (such as Acer saccharum or Sugar Maple) and occasionally with members of the Sapindaceae family. Patients allergic to one type of maple are frequently allergic to others.
> Important: Your healthcare provider will evaluate your complete medical history and perform lung function tests before prescribing Acer Rubrum Whole.
It is generally considered safe to continue Acer Rubrum Whole while breastfeeding. The large proteins in the extract are not expected to pass into breast milk in significant quantities, and even if they did, they would likely be digested by the infant's gastrointestinal tract. There are no known adverse effects on the nursing infant.
No dosage adjustment is needed. The proteins are processed by the immune system and cellular proteases, not the kidneys. However, ensure the patient is hemodynamically stable.
No dosage adjustment is needed. The liver does not play a primary role in the clearance of injected allergenic proteins.
> Important: Special populations require individualized medical assessment. Always inform your allergist if your health status or medications change.
Acer Rubrum Whole functions as an active immunotherapeutic agent. The primary allergens in Red Maple pollen are captured by antigen-presenting cells (APCs) at the site of injection. These APCs process the proteins into peptides and present them to T-lymphocytes. In an allergic individual, this usually results in a Th2 response. However, the controlled, increasing doses of Acer Rubrum Whole force the immune system to produce Regulatory T-cells (Tregs). These Tregs secrete IL-10, which induces B-cells to switch from producing IgE (the allergy antibody) to IgG4 (the blocking antibody). IgG4 acts as a 'buffer,' intercepting the maple pollen allergens before they can reach the IgE on mast cells.
| Parameter | Value |
|---|---|
| Bioavailability | N/A (Subcutaneous) |
| Protein Binding | N/A |
| Half-life (Proteins) | 2–12 hours |
| Tmax (Systemic) | 30–60 minutes |
| Metabolism | Cellular Proteolysis |
| Excretion | Not Renally Excreted |
Acer Rubrum Whole is an Allergenic Extract. It is grouped with other tree pollen extracts (e.g., Oak, Birch, Hickory) used in the diagnosis and treatment of Type I hypersensitivity disorders.
Medications containing this ingredient
Common questions about Acer Rubrum Whole
Acer Rubrum Whole is an allergenic extract used specifically for the diagnosis and treatment of allergies to Red Maple pollen. It is administered to patients who suffer from seasonal allergic rhinitis (hay fever), allergic conjunctivitis, or allergic asthma triggered by these trees. By giving the body small, increasing amounts of the allergen, the treatment helps the immune system become less sensitive over time. This process is known as immunotherapy or desensitization. It is not used for the immediate relief of symptoms but rather as a long-term disease-modifying therapy.
The most common side effects are local reactions at the site of the injection. These include redness, itching, swelling, and a small bump or 'wheal' where the needle entered the skin. These reactions usually appear within minutes and resolve within a few hours to a day. Some patients may also feel slightly tired or experience a mild flare-up of their typical allergy symptoms, like sneezing. While most local reactions are harmless, very large swellings should be reported to your doctor as they may require a dose adjustment.
There is no direct chemical interaction between alcohol and the proteins in Acer Rubrum Whole. However, healthcare providers generally recommend avoiding alcohol for several hours after an injection. Alcohol can cause blood vessels to dilate, which might speed up the absorption of the allergen into your bloodstream, potentially increasing the risk of a systemic reaction. Additionally, being under the influence of alcohol can make it harder for you to notice or accurately describe the early symptoms of an allergic reaction, which is a significant safety concern.
The safety of starting Acer Rubrum Whole during pregnancy has not been established, and it is generally categorized as FDA Category C. Most allergists will not start a new course of immunotherapy for a pregnant patient because of the risk of anaphylaxis, which can be dangerous for the baby. However, if a woman is already on a stable maintenance dose and is tolerating the injections well, her doctor may decide to continue the treatment. The decision is based on a careful balance between the risks of a reaction and the benefits of controlling the mother's allergy symptoms.
Immunotherapy with Acer Rubrum Whole is a slow process and does not provide instant relief like an antihistamine. Most patients begin to notice a significant reduction in their allergy symptoms after they reach the 'maintenance dose,' which usually takes 3 to 6 months of weekly injections. Maximum benefit is typically seen after the first full year of treatment. To ensure the results last for many years after the shots are stopped, a full course of 3 to 5 years of therapy is generally recommended by clinical guidelines.
Yes, you can stop taking Acer Rubrum Whole suddenly without experiencing a 'withdrawal' in the traditional sense. Since it is a biological extract that works by retraining your immune system, stopping the shots will not cause an immediate physical illness. However, if you stop before completing the recommended 3-5 year course, your allergy symptoms are likely to return over time as your immune system loses its desensitization. If you miss several doses and want to restart, you must consult your doctor, as your dose will likely need to be lowered for safety.
If you miss a dose of Acer Rubrum Whole, you should contact your allergist's office to reschedule as soon as possible. Do not attempt to take an extra dose later. The safety of immunotherapy depends on the timing of the doses; if too much time passes between injections, your sensitivity to the extract may increase. Depending on how many days or weeks have passed since your last shot, your doctor may need to repeat your last dose or even reduce the concentration to prevent a reaction when you restart.
There is no clinical evidence to suggest that Acer Rubrum Whole causes weight gain. The extract consists of small amounts of naturally occurring proteins and does not contain hormones, steroids, or calories that would affect your metabolism or appetite. If you experience weight gain while undergoing immunotherapy, it is likely due to other factors, such as the use of oral corticosteroids for asthma or other unrelated lifestyle changes. Always discuss unexpected weight changes with your primary care physician.
Acer Rubrum Whole can be taken with most standard medications, but there are critical exceptions. You must inform your doctor if you are taking beta-blockers (often used for heart conditions or migraines) or ACE inhibitors, as these can make allergic reactions much more dangerous and harder to treat. Most patients continue taking their daily allergy medications, like antihistamines or nasal sprays, while receiving immunotherapy. In fact, these medications can help manage the minor side effects of the shots, though they should be used consistently so they don't mask serious symptoms.
Acer Rubrum Whole is a biological product rather than a chemically synthesized drug, so the term 'generic' does not apply in the same way it does to pills like ibuprofen. However, various manufacturers produce Red Maple allergenic extracts. While they all contain the same basic pollen proteins, they are not always interchangeable because their concentrations and 'Allergy Units' may be measured differently. Your allergist will usually stick with one manufacturer's extract for your entire course of treatment to ensure the dosage remains consistent and safe.