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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Brand Name
Ad Overnight Healing
Generic Name
Ad Overnight Healing
Active Ingredient
PetrolatumCategory
Non-Standardized Chemical Allergen [EPC]
Variants
1
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| 47.2 g/100g | OINTMENT | TOPICAL | 65197-404 |
Detailed information about Ad Overnight Healing
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Ad Overnight Healing, you must consult a qualified healthcare professional.
Petrolatum is a highly effective occlusive skin protectant used to treat or prevent dry, rough, scaly, or itchy skin. It belongs to the class of emollients and works by forming an oily layer on the top of the skin that traps water in the skin.
For general skin protection and treatment of dry skin, Petrolatum should be applied topically to the affected area as needed. There is no maximum daily dose for topical application, though a thin layer is generally sufficient to provide an occlusive barrier.
Petrolatum is considered safe for use in infants, children, and adolescents. For diaper rash, apply Petrolatum with every diaper change, especially at bedtime or anytime when exposure to wet diapers may be prolonged. For general skin dryness, apply as needed.
No dosage adjustments are required as there is no systemic absorption.
No dosage adjustments are required.
No specific adjustments are necessary; however, elderly patients with fragile skin should apply the product gently to avoid mechanical trauma.
Since Petrolatum is used on an as-needed basis, missing a dose is not clinically significant. Apply it as soon as you remember if the skin feels dry or irritated.
Systemic overdose from topical application is virtually impossible. However, if the product is ingested, it may have a laxative effect. In cases of significant oral ingestion, contact a poison control center. If inhaled (aspiration), seek immediate medical attention as it can cause lipid pneumonia.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose without medical guidance.
> Warning: Stop using Petrolatum and call your doctor immediately if you experience any of these:
Prolonged use on healthy skin is generally safe. However, chronic use in intertriginous areas (skin folds) may lead to skin breakdown or fungal infections due to excessive moisture trapping.
No FDA black box warnings exist for Petrolatum. It is widely recognized as safe (GRAS) for its intended topical uses.
Report any unusual symptoms to your healthcare provider.
Petrolatum is for external use only. It should not be used on deep or puncture wounds, animal bites, or serious burns unless directed by a healthcare professional.
No FDA black box warnings for Petrolatum.
There are no specific laboratory monitoring requirements (e.g., blood tests) for the use of topical Petrolatum. Patients should monitor the skin for signs of improvement or secondary infection.
Petrolatum does not affect the ability to drive or operate machinery. However, if applied to the hands, it may cause a slippery grip.
There are no known interactions between topical Petrolatum and alcohol consumption.
Petrolatum can be stopped at any time without a tapering schedule. If being used for a chronic condition like eczema, discontinuation may result in a return of skin dryness.
> Important: Discuss all your medical conditions with your healthcare provider before starting Petrolatum.
There are no known systemic drug-drug contraindications for topical Petrolatum. However, it should not be used simultaneously with latex condoms or diaphragms if applied to the genital area, as petroleum products can weaken latex and lead to contraceptive failure or increased STI risk.
There are no known food interactions with topically applied Petrolatum.
No significant interactions with herbal supplements have been documented for topical Petrolatum.
Petrolatum does not typically interfere with standard blood or urine laboratory tests. It may interfere with the results of certain skin patch tests if not properly cleaned from the site.
For each major interaction, explain:
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking.
There is little evidence of cross-sensitivity between Petrolatum and other hydrocarbons, but patients with multiple chemical sensitivities should perform a small spot test first.
> Important: Your healthcare provider will evaluate your complete medical history before prescribing Petrolatum.
FDA Pregnancy Category: Not formally assigned (Topical). Since Petrolatum is not absorbed systemically, it is considered safe for use during all trimesters of pregnancy. There is no known risk of teratogenicity or adverse developmental effects.
Petrolatum is safe for use during breastfeeding. However, if applied to the breast or nipple area, it should be thoroughly cleaned off before nursing to prevent the infant from ingesting the product or slipping during latching.
Approved for use in infants and children of all ages. It is a first-line recommendation for the prevention of diaper rash and the management of pediatric atopic dermatitis (eczema).
Highly effective for geriatric xerosis (dry skin). Care should be taken to avoid application to the soles of the feet, as this can significantly increase the risk of falls due to slipperiness.
No dosage adjustments are needed. It is safe for patients on dialysis.
No dosage adjustments are needed as the drug is not metabolized by the liver.
> Important: Special populations require individualized medical assessment.
Petrolatum acts as an occlusive emollient. It creates an epicutaneous (on top of the skin) film that serves as a physical substitute for the skin's natural lipid barrier. This film prevents the evaporation of water from the stratum corneum to the external environment. By maintaining a high water content in the skin, it promotes the desquamation (shedding) of dead skin cells and improves the flexibility and integrity of the skin surface.
The effects of Petrolatum are immediate upon application. The duration of effect lasts until the product is physically removed or absorbed into the very top layers of dead skin cells. It does not have systemic pharmacological effects and does not bind to receptors.
| Parameter | Value |
|---|---|
| Bioavailability | 0% (Topical, intact skin) |
| Protein Binding | N/A |
| Half-life | N/A (Non-systemic) |
| Tmax | N/A |
| Metabolism | None |
| Excretion | Physical removal |
Petrolatum is classified as a Skin Protectant and Occlusive Emollient. It is often grouped with other protectants like zinc oxide or dimethicone in dermatological therapy.
Common questions about Ad Overnight Healing
Petrolatum is primarily used as a skin protectant to treat and prevent dry, rough, or scaly skin. It is highly effective for relieving chapped lips, protecting minor cuts and burns, and managing diaper rash in infants. By forming an occlusive barrier, it prevents moisture loss and protects the skin from environmental irritants like wind or cold. Healthcare providers often recommend it as a base for wound healing after minor dermatological procedures. It is also a key component in managing chronic conditions like eczema and psoriasis by restoring the skin barrier.
The most common side effects of Petrolatum are related to its physical properties rather than chemical toxicity. Users often report a greasy or sticky feeling on the skin, which some find uncomfortable. If applied to hair-bearing areas, it can cause folliculitis, which appears as small red bumps around the hair follicles. In some individuals, it may lead to 'heat rash' by trapping sweat under the skin. While it is non-irritating for most, excessive use in skin folds can lead to skin maceration or softening.
Yes, you can consume alcohol while using topical Petrolatum. Since Petrolatum is applied to the skin and is not absorbed into the bloodstream, there is no interaction between the two substances. Alcohol does not affect how the skin protectant works, and Petrolatum does not change how the body processes alcohol. However, excessive alcohol consumption can dehydrate the skin, which may counteract the benefits of using an emollient. Always follow general health advice regarding alcohol use provided by your doctor.
Petrolatum is considered very safe for use during pregnancy. Because it remains on the surface of the skin and is not absorbed systemically, there is no risk of the product reaching the developing fetus. It is frequently used by pregnant women to help manage dry skin or to soothe the skin on the abdomen. No studies have shown any link between topical petrolatum use and birth defects or other pregnancy complications. As with any product, if you have concerns, you should discuss them with your obstetrician.
Petrolatum begins working immediately upon application by creating a physical barrier that traps moisture. You will likely feel an immediate softening of the skin and relief from dryness or itching. For healing of chapped skin or minor wounds, significant improvement is typically seen within 24 to 48 hours of consistent use. For chronic dry skin conditions, it may take several days of regular application to fully restore the skin barrier. If your skin condition does not improve within seven days, consult a healthcare provider.
Yes, you can stop using Petrolatum at any time without experiencing withdrawal symptoms or physical 'rebound' effects. Unlike some medicated creams, such as topical steroids, Petrolatum does not alter the skin's internal physiology. However, if you are using it to manage a chronic condition like eczema, your skin may become dry or itchy again once the protective barrier is removed. It is generally safe to use Petrolatum long-term as part of a daily skincare routine. Talk to your dermatologist about the best maintenance plan for your skin.
If you miss an application of Petrolatum, simply apply it as soon as you remember or when your skin feels dry. Because Petrolatum is not a systemic medication, there is no danger in missing a dose or changing the timing of application. You do not need to apply 'double' the amount to make up for a missed dose. Regular application, especially after washing or bathing, provides the best results for maintaining skin hydration. Follow the schedule suggested by your healthcare provider for specific skin conditions.
No, Petrolatum does not cause weight gain. It is a topical skin protectant that is not absorbed into the body's systemic circulation or metabolic pathways. It contains no calories that the body can process, and it does not affect hormones or appetite. Any changes in weight while using Petrolatum would be unrelated to the product itself. If you experience unexplained weight gain, you should consult your healthcare provider to determine the underlying cause.
Petrolatum is generally safe to use alongside other medications, but its occlusive nature can affect how other topical drugs work. If you apply Petrolatum over a prescription cream, it may increase the absorption and potency of that medication, which could lead to side effects. Conversely, if you apply Petrolatum first, it may prevent other creams from reaching the skin surface. It is usually best to apply medicated creams first, let them absorb, and then apply Petrolatum as a 'sealer.' Always inform your doctor about all topical products you are using.
Petrolatum is widely available as a generic product, often labeled simply as 'White Petrolatum' or 'Petroleum Jelly.' It is the active ingredient in many well-known brand-name products like Vaseline. Generic versions are required by the FDA to meet the same standards for purity and effectiveness as brand-name versions. Because it is an inexpensive hydrocarbon mixture, generic versions are highly cost-effective and readily available at most pharmacies and grocery stores. There is typically no clinical difference between generic and brand-name 100% white petrolatum.
Other drugs with the same active ingredient (Petrolatum)