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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Brand Name
Aralia Racemosa
Generic Name
Aralia Racemosa
Active Ingredient
Aralia Racemosa RootCategory
alpha-Adrenergic Agonist [EPC]
Variants
7
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Aralia Racemosa, you must consult a qualified healthcare professional.
| 30 [hp_C]/1 | PELLET | ORAL | 63545-082 |
| 6 [hp_C]/1 | PELLET | ORAL | 63545-080 |
| 500 [hp_C]/1 | PELLET | ORAL | 63545-085 |
| 100 [hp_C]/1 | PELLET | ORAL | 63545-083 |
Detailed information about Aralia Racemosa
Aralia Racemosa Root is a complex botanical extract classified as an alpha-adrenergic agonist and a non-standardized plant allergenic extract, primarily used in the management of respiratory symptoms and allergic sensitivities.
Dosage for Aralia Racemosa Root varies significantly based on the formulation and the specific condition being treated.
Aralia Racemosa Root should be used in children only under the direct supervision of a pediatrician or qualified healthcare provider.
Because a significant portion of the metabolites are excreted renally, patients with a Creatinine Clearance (CrCl) below 30 mL/min should use Aralia Racemosa Root with caution. A 50% dose reduction may be considered to prevent accumulation of phytochemical constituents.
In cases of severe hepatic impairment (Child-Pugh Class C), the metabolism of diterpene acids may be slowed. Monitoring for increased side effects (such as tachycardia) is recommended, and lower starting doses are advised.
Geriatric patients may be more sensitive to the alpha-adrenergic effects of the root. Healthcare providers typically start at the lower end of the dosing spectrum to minimize the risk of hypertension or urinary retention.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up, as this may increase the risk of adrenergic side effects.
Signs of an overdose of Aralia Racemosa Root (particularly concentrated extracts) may include:
In the event of a suspected overdose, contact your local poison control center or seek emergency medical attention immediately. If an overdose occurs during an immunotherapy injection, emergency protocols for anaphylaxis (including epinephrine) must be initiated by the medical staff.
> Important: Follow your healthcare provider's dosing instructions precisely. Do not adjust your dose or frequency without medical guidance, especially when using allergenic extracts.
Most patients tolerate Aralia Racemosa Root well, especially in homeopathic dilutions. However, when using more concentrated forms or during the initial stages of immunotherapy, the following may occur:
Aralia Racemosa Root is a potent pharmacological agent that affects the autonomic nervous system and the immune system. It should never be viewed as 'just a natural root' without clinical consequences. Patients with underlying cardiovascular conditions or severe allergies must exercise extreme caution.
There are no specific FDA black box warnings for Aralia Racemosa Root as an individual ingredient. However, when utilized as part of a Non-Standardized Plant Allergenic Extract, it falls under the general safety mandates for immunotherapy. These mandates state that the extract must be administered by physicians trained in the treatment of anaphylaxis and that the patient must remain under medical observation for a minimum of 30 minutes post-injection.
Aralia Racemosa Root must NEVER be used in the following circumstances:
Aralia Racemosa Root is currently classified as Category C (or equivalent). There are no adequate and well-controlled studies in pregnant women. Animal reproduction studies have not been conducted.
It is unknown whether the active constituents of Aralia Racemosa Root are excreted in human milk. Because many phytochemicals and small molecules do pass into breast milk, and because the infant's adrenergic system is highly sensitive, use during breastfeeding is not recommended. If a nursing mother must use the drug, the infant should be monitored for signs of irritability, tachycardia, or changes in sleep patterns.
Aralia Racemosa Root functions primarily as a peripheral alpha-adrenergic agonist. The active diterpene acids and saponins are thought to interact with alpha-1 receptors on vascular smooth muscle cells. This interaction stimulates the phospholipase C pathway, leading to the production of inositol trisphosphate (IP3) and the release of calcium from the sarcoplasmic reticulum. The resulting increase in intracellular calcium causes muscle contraction and vasoconstriction.
Additionally, the extract possesses beta-adrenergic properties, likely acting on beta-2 receptors in the lungs to stimulate adenylate cyclase, increasing cAMP levels and promoting bronchodilation. Its role as an allergenic extract involves the modulation of the cytokine profile, specifically reducing IL-4 and IL-5 production while increasing IFN-gamma, which helps rebalance the immune system away from an allergic state.
Common questions about Aralia Racemosa
Aralia Racemosa Root is primarily used to manage symptoms of allergic rhinitis, such as hay fever, sneezing, and watery nasal discharge. In clinical pharmacology, it is classified as an alpha-adrenergic agonist, meaning it helps to constrict blood vessels in the nasal passages to reduce swelling and congestion. It is also used by allergists as a non-standardized plant allergenic extract for diagnostic skin testing and immunotherapy. Some traditional and homeopathic applications include treating a specific type of 'night cough' or asthmatic symptoms that worsen when lying down. Always consult a healthcare provider to see if this specific extract is appropriate for your respiratory or allergic condition.
The most common side effects of Aralia Racemosa Root include dry mouth, mild nausea, and local irritation if administered as an injection. Because of its adrenergic properties, some patients may experience a slight increase in heart rate (palpitations) or a mild headache. In homeopathic dilutions, side effects are rare but can include a temporary 'aggravation' or worsening of symptoms before improvement occurs. If used as an allergenic extract, redness and itching at the injection site are very common. It is important to report any persistent or bothersome side effects to your doctor immediately.
It is generally advised to avoid or strictly limit alcohol consumption while taking Aralia Racemosa Root. Alcohol acts as a vasodilator, which can counteract the vasoconstrictive (vessel-narrowing) effects that Aralia is intended to produce for congestion relief. Furthermore, alcohol can increase the risk of dizziness and gastrointestinal upset when combined with botanical extracts. There is also a concern that alcohol might mask the early symptoms of a serious allergic reaction, making it harder to seek timely medical help. Discuss your alcohol intake with your healthcare provider to ensure it does not interfere with your treatment plan.
Aralia Racemosa Root is not recommended for use during pregnancy unless a physician determines that the benefits clearly outweigh the potential risks to the fetus. It is classified in a category indicating a lack of high-quality human studies, and some of its chemical components may have theoretical effects on uterine tone. There is no definitive data regarding its safety during organogenesis in the first trimester or its effects on late-term pregnancy. Pregnant women should always consult their obstetrician before starting any new medication, including herbal or homeopathic remedies. Safety during breastfeeding is also unestablished, and caution is advised.
The time it takes for Aralia Racemosa Root to work depends on the form being used and the condition being treated. For acute relief of nasal congestion or cough using oral dilutions, patients may notice an improvement within 30 to 60 minutes. However, when used as part of an allergenic immunotherapy program to desensitize the immune system, it can take several months of regular treatment to see a significant reduction in allergy symptoms. Consistent dosing as prescribed by your healthcare provider is key to achieving the desired therapeutic outcome. If symptoms do not improve within a week of acute use, contact your doctor.
For most patients using homeopathic or low-dose supplement forms, stopping Aralia Racemosa Root suddenly does not cause severe withdrawal symptoms. However, if you have been using concentrated extracts for a long period, sudden discontinuation might lead to a 'rebound' effect where nasal congestion or respiratory symptoms temporarily return with greater intensity. If you are undergoing immunotherapy injections, stopping suddenly will halt the desensitization process and may require you to start the 'build-up' phase over again. It is always best to consult your healthcare provider before stopping any long-term medication to ensure a safe and effective transition.
If you miss a dose of Aralia Racemosa Root, you should take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular timing. You should never take two doses at once to make up for a missed one, as this can increase the risk of adrenergic side effects like a rapid heart rate or increased blood pressure. If you are receiving immunotherapy injections and miss an appointment, contact your allergist immediately, as your next dose may need to be adjusted downward for safety. Consistency is vital for the effectiveness of this treatment.
There is currently no clinical evidence to suggest that Aralia Racemosa Root causes weight gain. Unlike some other medications used for allergies, such as certain corticosteroids or older antihistamines, Aralia's mechanism as an alpha-adrenergic agonist does not typically interfere with metabolic rate or appetite regulation. Most side effects are related to the autonomic nervous system, such as dry mouth or heart rate changes, rather than metabolic shifts. If you experience unexplained weight gain while taking this medication, it is likely due to another factor, and you should discuss it with your healthcare provider.
Aralia Racemosa Root can interact with several other medications, so caution is necessary. It should never be taken with MAO inhibitors, as this can cause a dangerous spike in blood pressure. It may also interact with blood pressure medications, beta-blockers, and other stimulants or decongestants. Combining it with other herbal supplements that affect the heart or nervous system, such as Ephedra or Ginseng, can also be risky. Always provide your doctor or pharmacist with a full list of all prescription drugs, over-the-counter medicines, and supplements you are taking to prevent potentially harmful interactions.
Aralia Racemosa Root is primarily available as a botanical extract, homeopathic remedy, or non-standardized allergenic extract rather than a conventional 'brand-name vs. generic' prescription drug. It is sold under various labels by different homeopathic and supplement manufacturers. In the context of immunotherapy, it is often part of a customized allergenic extract prepared by specialized laboratories. While there is no single 'brand' that holds a patent, the quality and concentration can vary between manufacturers. It is important to use a reputable source and follow the specific product instructions provided by your healthcare professional.
Other drugs with the same active ingredient (Aralia Racemosa Root)
> Warning: Stop taking Aralia Racemosa Root and call your doctor immediately if you experience any of these serious symptoms.
Prolonged use of Aralia Racemosa Root as an adrenergic agonist may lead to 'tachyphylaxis' or a diminished response to the drug. There is also a theoretical risk of 'rebound congestion' (rhinitis medicamentosa) if used excessively for nasal symptoms, similar to other alpha-agonists like oxymetazoline. Long-term safety studies exceeding 12 months of continuous use are lacking; therefore, periodic 'drug holidays' or reassessments by a healthcare provider are recommended.
No FDA black box warnings currently exist specifically for Aralia Racemosa Root in its homeopathic or dietary supplement forms. However, for Allergenic Extracts (which may include Aralia Racemosa), the FDA requires a general warning regarding the risk of severe systemic allergic reactions, including anaphylaxis. These products must only be administered in settings equipped with emergency supplies, including epinephrine, and patients must be observed for at least 30 minutes following administration.
Report any unusual symptoms or persistent side effects to your healthcare provider. You may also report side effects to the FDA at 1-800-FDA-1088.
Patients undergoing long-term therapy or immunotherapy with Aralia Racemosa Root should have the following monitored:
While Aralia Racemosa Root does not typically cause sedation, its potential to cause dizziness or transient changes in blood pressure may impair your ability to operate heavy machinery or drive safely. Observe your reaction to the medication for several days before engaging in these activities.
Alcohol should be avoided or strictly limited. Alcohol can dilate blood vessels, which may counteract the vasoconstrictive therapeutic goals of Aralia Racemosa Root. Furthermore, alcohol may increase the risk of gastrointestinal irritation and may mask the early signs of an allergic reaction.
Do not stop taking Aralia Racemosa Root suddenly if you have been using it for a prolonged period at high doses. While it does not have a formal 'withdrawal syndrome,' sudden cessation of an adrenergic agonist can lead to rebound symptoms, such as increased nasal congestion or a temporary drop in blood pressure. A gradual tapering over 1-2 weeks is generally recommended under medical supervision.
> Important: Discuss all your medical conditions, especially heart disease and asthma, with your healthcare provider before starting Aralia Racemosa Root.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking. A complete medication reconciliation is essential for safety.
Conditions requiring careful risk-benefit analysis by a physician:
Patients should be aware of potential cross-sensitivity with:
> Important: Your healthcare provider will evaluate your complete medical history, including any history of 'panic attacks' or 'heart palpitations,' before prescribing Aralia Racemosa Root.
Aralia Racemosa Root is not FDA-approved for general use in children under the age of 6. For children over 6, it is primarily used in homeopathic dilutions or under strict allergenic extract protocols.
Patients over the age of 65 are at a higher risk for adverse effects.
In patients with moderate to severe renal impairment, the elimination half-life of Aralia's metabolites is likely prolonged.
Since the liver is responsible for the Phase I and Phase II metabolism of the root's diterpenes, patients with cirrhosis or hepatitis may experience increased systemic exposure. Dose adjustments should be based on the Child-Pugh score, with significant reductions (50%) for those in Class B or C.
> Important: Special populations require individualized medical assessment and frequent follow-up to ensure safety and efficacy.
| Parameter | Value |
|---|---|
| Bioavailability | 15-25% (oral) |
| Protein Binding | 60-75% |
| Half-life | 4-8 hours |
| Tmax | 1.5 - 2 hours |
| Metabolism | Hepatic (CYP3A4, Glucuronidation) |
| Excretion | Renal 65%, Fecal 35% |
Aralia Racemosa Root is classified as an alpha-Adrenergic Agonist [EPC] and a Non-Standardized Plant Allergenic Extract [EPC]. It shares therapeutic space with other adrenergic agents like phenylephrine, though its botanical origin and immunological applications provide a broader clinical utility in integrative medicine.