Loading...
Loading...
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Glycerin
Brand Name
Eelhoe Skin Advanced Mole Remove Serum
Generic Name
Glycerin
Active Ingredient
Hamamelis Virginiana (witch Hazel) Leaf WaterCategory
Amide Local Anesthetic [EPC]
Variants
1
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| .006 mg/30mg | LIQUID | TOPICAL | 85064-012 |
Detailed information about Eelhoe Skin Advanced Mole Remove Serum
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Eelhoe Skin Advanced Mole Remove Serum, you must consult a qualified healthcare professional.
Hamamelis Virginiana (Witch Hazel) Leaf Water is a botanical astringent and skin protectant, classified in some regulatory contexts as an Amide Local Anesthetic [EPC] for its soothing properties on cutaneous nerve endings.
For general skin irritation, insect bites, or minor cuts, Hamamelis Virginiana (Witch Hazel) Leaf Water should be applied topically to the affected area as needed.
No dosage adjustments are required for patients with renal impairment. Because the drug is applied topically and has negligible systemic absorption, the kidneys are not significantly involved in its clearance.
No dosage adjustments are required for patients with hepatic impairment. The lack of systemic bioavailability ensures that liver function does not impact the safety or efficacy of the product.
Elderly patients may use Hamamelis Virginiana Leaf Water safely. However, clinicians should note that older skin is often thinner and more prone to dryness. Frequent application may lead to localized xerosis (dry skin), and the frequency of use should be monitored.
Hamamelis Virginiana Leaf Water is for EXTERNAL USE ONLY.
Since this medication is typically used on an 'as-needed' basis for symptom relief, a missed dose is not clinically significant. If you are following a specific schedule recommended by your doctor, apply the missed dose as soon as you remember. If it is almost time for the next application, skip the missed dose and resume your regular schedule. Do not 'double up' the amount of solution used.
Systemic overdose from topical application is virtually impossible. However, accidental ingestion can occur, particularly in pediatric populations.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose or apply to large areas of the body without medical guidance.
Hamamelis Virginiana (Witch Hazel) Leaf Water is exceptionally well-tolerated by the vast majority of users. However, the most common side effect reported is Localized Skin Dryness.
While systemic reactions are extremely rare for topical Witch Hazel, they can occur if the product is applied to denuded (stripped) skin over large surface areas or if an anaphylactic response occurs.
> Warning: Stop taking Hamamelis Virginiana (Witch Hazel) Leaf Water and call your doctor immediately if you experience any of these:
Prolonged use of Hamamelis Virginiana Leaf Water on the face as a toner may lead to chronic dryness and a disruption of the skin's natural lipid barrier. In some cases, this can lead to 'rebound' oiliness, where the skin produces more sebum to compensate for the dryness caused by the astringent. Long-term use on the anorectal area is generally safe, but chronic irritation should always be evaluated by a gastroenterologist to rule out more serious pathology like inflammatory bowel disease (IBD).
No FDA black box warnings have been issued for Hamamelis Virginiana (Witch Hazel) Leaf Water. It is considered a Category I (GRASE - Generally Recognized as Safe and Effective) ingredient under the FDA OTC Monograph for its intended uses.
Report any unusual symptoms to your healthcare provider. If you suspect you are having a serious reaction, seek emergency care immediately.
Hamamelis Virginiana (Witch Hazel) Leaf Water is intended for topical use only. It must never be taken orally, used in the eyes, or injected. If the product enters the eyes, rinse thoroughly with cool water for at least 15 minutes. If irritation persists, seek ophthalmic evaluation.
No FDA black box warnings for Hamamelis Virginiana (Witch Hazel) Leaf Water. It is one of the most widely used and safest botanical ingredients in the pharmaceutical industry.
Because there is no significant systemic absorption, routine laboratory monitoring (such as blood counts, liver function tests, or kidney function tests) is not required for patients using Hamamelis Virginiana Leaf Water. Clinical monitoring should focus on the appearance of the skin or mucous membranes at the site of application to ensure the condition is resolving and no secondary infection is developing.
Hamamelis Virginiana Leaf Water does not cross the blood-brain barrier and has no known effect on the central nervous system. It is safe to drive or operate heavy machinery while using this medication.
There are no known contraindications regarding the consumption of alcohol while using topical Witch Hazel. However, users should be aware that some Witch Hazel products contain alcohol as a preservative, which can be drying to the skin.
There are no tapering requirements for Hamamelis Virginiana Leaf Water. You may stop using the product at any time without risk of withdrawal symptoms or rebound effects, other than the potential return of the original symptoms (e.g., itching or swelling) if the underlying cause has not been resolved.
> Important: Discuss all your medical conditions with your healthcare provider before starting Hamamelis Virginiana (Witch Hazel) Leaf Water, especially if you have chronic skin conditions like eczema or psoriasis.
There are no known absolute contraindications for drug-drug interactions with Hamamelis Virginiana (Witch Hazel) Leaf Water due to its topical nature and lack of systemic absorption. However, it should not be applied simultaneously with other topical medications on the same patch of skin unless directed by a doctor, as the astringent properties of Witch Hazel could potentially alter the absorption of the other drug.
There are no known interactions between Hamamelis Virginiana Leaf Water and food or beverages. Unlike many oral medications, its efficacy is not affected by grapefruit juice, dairy, or high-fat meals.
Hamamelis Virginiana Leaf Water does not interfere with standard blood, urine, or imaging tests. It does not affect glucose monitoring, coagulation studies (PT/INR), or cardiac enzymes.
For each major interaction, the mechanism is typically a pharmacodynamic interaction at the skin surface (additive irritation) rather than a pharmacokinetic interaction (CYP450 metabolism). The management strategy is usually to stagger application times or reduce the frequency of use.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking, even those applied to the skin.
Hamamelis Virginiana (Witch Hazel) Leaf Water must NEVER be used in the following circumstances:
Conditions requiring careful risk-benefit analysis include:
There is a theoretical risk of cross-sensitivity for patients allergic to other members of the Hamamelidaceae family (such as Loropetalum or Parrotia). However, this is rarely seen in clinical practice. Patients who are sensitive to various botanical distillates should perform a 'patch test' on a small area of skin for 24 hours before widespread use.
> Important: Your healthcare provider will evaluate your complete medical history, including any history of skin allergies, before recommending Hamamelis Virginiana (Witch Hazel) Leaf Water for therapeutic use.
Hamamelis Virginiana Leaf Water is widely used by pregnant women for the management of pregnancy-related hemorrhoids and leg edema. Because systemic absorption is negligible, it is not expected to pose a risk to the developing fetus. There are no known reports of teratogenicity (birth defects) associated with the topical use of Witch Hazel. However, as with all medications during pregnancy, it should be used only when clearly needed and under the guidance of a healthcare provider, especially in the first trimester.
Witch Hazel is considered compatible with breastfeeding. There is no evidence to suggest that the topical application of Hamamelis Virginiana Leaf Water to the mother results in detectable levels in breast milk. If applying to the breast area for skin irritation, the mother should ensure the area is thoroughly cleaned before nursing to prevent the infant from accidentally ingesting the product.
Witch Hazel is approved for use in children 12 years of age and older. For children under 12, a physician should be consulted. While not inherently toxic, children have a higher surface-area-to-body-mass ratio, and their skin is more permeable. Excessive use of alcohol-containing Witch Hazel on infants can lead to localized irritation or, in extreme cases of large-scale application, theoretical alcohol absorption.
Older adults can use Witch Hazel safely. The primary concern in this population is the increased fragility of the skin (senile purpura and skin atrophy). Geriatric patients should be advised to use the product sparingly to avoid over-drying, which can lead to skin fissures and secondary infections. There are no specific concerns regarding polypharmacy, as Witch Hazel does not interact with systemic medications commonly taken by the elderly (e.g., blood thinners, blood pressure medications).
No dose adjustment is necessary for patients with any degree of renal impairment, including those on hemodialysis. The active components do not reach the systemic circulation in quantities that would require renal clearance.
No dose adjustment is necessary for patients with hepatic impairment (Child-Pugh Class A, B, or C). The liver is not involved in the processing of this topically applied botanical water.
> Important: Special populations, particularly pregnant women and those with chronic skin conditions, require individualized medical assessment to ensure the safest possible treatment plan.
Hamamelis Virginiana (Witch Hazel) Leaf Water exerts its therapeutic effects through a high concentration of phytochemicals, including hamamelitannin, proanthocyanidins, and volatile oils (such as hexenol and ionone). The primary mechanism is astringency. When applied to the skin, the tannins and phenolic compounds form cross-links with surface proteins. This causes the proteins to coagulate, which physically 'shrinks' the tissue and tightens the skin's surface.
Additionally, its classification as an Amide Local Anesthetic [EPC] in specific regulatory data suggests a stabilizing effect on the cell membranes of local sensory neurons. By reducing the local inflammatory response and stabilizing capillary walls (decreasing 'leakiness'), it effectively numbs the sensation of itching and minor pain. It also acts as a mild vasoconstrictor, reducing blood flow to the area, which helps decrease redness and swelling.
| Parameter | Value |
|---|---|
| Bioavailability | <1% (Negligible) |
| Protein Binding | High (Local tissue proteins) |
| Half-life | N/A (Topical/Local) |
| Tmax | N/A (Local effect) |
| Metabolism | Minimal (Skin esterases) |
| Excretion | Physical (Desquamation) |
Hamamelis Virginiana Leaf Water is classified as a Topical Astringent and Skin Protectant. Within the EPC (Established Pharmacologic Class) system, it is categorized alongside Amide Local Anesthetics and Antiarrhythmics, reflecting its membrane-stabilizing and tissue-contracting properties. Related medications include Aluminum Acetate (Burow's Solution) and Zinc Oxide, though Witch Hazel is unique as a botanical distillate.
Common questions about Eelhoe Skin Advanced Mole Remove Serum
Hamamelis Virginiana (Witch Hazel) Leaf Water is primarily used as a topical astringent to relieve minor skin irritations, insect bites, and the discomfort associated with hemorrhoids. It works by causing the skin tissues to contract, which helps reduce swelling and inflammation while providing a protective barrier. Many people also use it as a facial toner to remove excess oil and tighten the appearance of pores. It is a versatile botanical product recognized by the FDA for its safety and efficacy in over-the-counter skin protectant products. However, it should only be used externally and never applied to deep or infected wounds.
The most common side effect of Hamamelis Virginiana Leaf Water is localized skin dryness or a feeling of tightness. Because it is an astringent designed to remove oils and shrink tissues, it can lead to flaking or mild peeling if used too frequently, especially on sensitive skin. Some users may also experience a brief stinging or burning sensation upon application, particularly if the product contains alcohol. Rare allergic reactions, such as redness or a rash, can occur in individuals sensitive to the Witch Hazel plant. If you notice severe irritation or blistering, you should discontinue use and consult a healthcare provider.
Yes, there are no known interactions between the consumption of alcoholic beverages and the topical use of Hamamelis Virginiana Leaf Water. Since the product is applied to the skin and has negligible systemic absorption, it does not enter the bloodstream in quantities that would interact with alcohol in your system. However, it is important to remember that Witch Hazel itself is for external use only and should never be ingested. Some commercial Witch Hazel preparations contain small amounts of ethanol as a preservative, but this does not affect the safety of drinking alcohol moderately while using the product as directed.
Hamamelis Virginiana Leaf Water is generally considered safe for use during pregnancy, particularly for managing common issues like hemorrhoids or skin rashes. Because it is applied topically and very little of the active ingredient reaches the bloodstream, it is unlikely to affect a developing fetus. Many obstetricians recommend Witch Hazel pads as a safe, non-drug option for postpartum recovery and comfort. However, it is always best to consult with your healthcare provider before starting any new treatment during pregnancy. They can help ensure that your specific symptoms are not a sign of a condition that requires more intensive medical management.
The effects of Hamamelis Virginiana Leaf Water are typically felt almost immediately after application. The cooling sensation and the physical tightening of the skin occur within seconds as the solution begins to evaporate and the tannins interact with surface proteins. For inflammatory conditions like insect bites or hemorrhoids, you may notice a reduction in itching and swelling within a few minutes. While the immediate relief is transient, regular application as directed can help manage symptoms throughout the day. If your symptoms do not improve after seven days of consistent use, you should seek medical advice to rule out other issues.
Yes, you can stop using Hamamelis Virginiana Leaf Water at any time without any risk of withdrawal or adverse effects. It is not a systemic medication and does not create a physical dependency or 'rebound' effect in the traditional sense. If you were using it for a specific condition like an itchy rash, the symptoms might return once you stop applying the astringent if the underlying cause has not been resolved. There is no need to taper the dose or slowly reduce its use. Simply discontinue use whenever your symptoms have cleared or if you experience any unwanted skin irritation.
If you miss a dose of Hamamelis Virginiana Leaf Water, simply apply it as soon as you remember if you still feel the need for symptom relief. Since this product is most often used on an as-needed basis for comfort, missing a dose is not a cause for concern and will not impact the overall effectiveness of the treatment. You do not need to apply extra solution to make up for the missed application. Just continue with your regular routine or use it the next time you experience itching or discomfort. If your doctor has given you a specific schedule, try to stick to it as closely as possible for the best results.
No, Hamamelis Virginiana Leaf Water does not cause weight gain. It is a topical botanical extract that acts locally on the surface of the skin and does not have any systemic metabolic effects. It does not contain calories that are absorbed by the body, nor does it affect hormones or appetite-regulating centers in the brain. Any changes in weight you may experience while using this product would be unrelated to the Witch Hazel itself. If you are concerned about unexpected weight changes, it is important to discuss them with your doctor to identify other potential causes related to diet, lifestyle, or other health conditions.
Hamamelis Virginiana Leaf Water is generally safe to use alongside most oral medications because it is not absorbed into the bloodstream. However, you should be cautious when using it at the same time as other topical creams or ointments. Because Witch Hazel is an astringent, it can dry the skin or change how other topical drugs are absorbed if they are applied to the same area. It is best to wait at least 30 minutes between applying Witch Hazel and any other medicated skin product. Always inform your doctor about all the products you use, including herbal remedies and over-the-counter skin treatments, to ensure there are no conflicts.
Yes, Hamamelis Virginiana Leaf Water is widely available as a generic product, often simply labeled as 'Distilled Witch Hazel' or 'Witch Hazel USP.' Generic versions are chemically equivalent to brand-name products and are required to meet the same FDA standards for purity and strength. You can find these generic versions in almost any pharmacy, grocery store, or health food shop. They are typically much less expensive than branded cosmetic versions while providing the same therapeutic benefits for skin irritation and hemorrhoid relief. When buying generic, check the label to ensure it does not contain added fragrances or dyes if you have sensitive skin.