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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Drosera, Arnica Montana, Bryonia, Cetraria Islandica, Coccus Cacti, Corallium Rubrum, Stannum Metallicum, Chamomilla, Coffee Crudea
Brand Name
Kids Relief
Generic Name
Drosera, Arnica Montana, Bryonia, Cetraria Islandica, Coccus Cacti, Corallium Rubrum, Stannum Metallicum, Chamomilla, Coffee Crudea
Active Ingredient
Arabica Coffee BeanCategory
Non-Standardized Food Allergenic Extract [EPC]
Variants
2
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| 4 [hp_C]/100mL | LIQUID | ORAL | 63388-915 |
| 4 [hp_C]/100mL | LIQUID | ORAL | 71971-9151 |
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Kids Relief, you must consult a qualified healthcare professional.
Detailed information about Kids Relief
Arabica Coffee Bean (Coffea arabica) is clinically utilized as a non-standardized food and plant allergenic extract and is the primary source of caffeine, a potent methylxanthine and central nervous system stimulant.
Dosage for Arabica Coffee Bean products varies significantly based on the intended use—diagnostic versus therapeutic.
Arabica Coffee Bean extracts for allergy testing can be used in children under the strict supervision of a pediatric allergist. Therapeutic use of caffeine derivatives in children is highly specialized:
While the parent compounds are mostly metabolized by the liver, the metabolites are cleared by the kidneys. In patients with severe renal impairment (kidney failure), the accumulation of metabolites may occur. Healthcare providers may suggest lower doses or longer intervals between doses.
Because the CYP1A2 enzyme system in the liver is responsible for nearly all metabolism, patients with cirrhosis or hepatitis will experience a significantly prolonged half-life. Doses should be reduced by 50% or more in patients with moderate-to-severe hepatic impairment to avoid toxicity.
Older adults are often more sensitive to the stimulant effects of Arabica Coffee Bean. Lower initial doses are recommended to avoid insomnia, tachycardia (fast heart rate), and tremors.
If a therapeutic dose is missed, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double the dose to make up for a missed one, as this significantly increases the risk of cardiovascular side effects.
Signs of Arabica Coffee Bean (caffeine) overdose include:
In case of suspected overdose, contact a poison control center or seek emergency medical attention immediately. Emergency measures may include gastric lavage (stomach pumping), activated charcoal, and supportive care for cardiac and neurological symptoms.
> Important: Follow your healthcare provider's dosing instructions precisely. Do not adjust your dose or use extracts for self-testing without medical guidance.
When Arabica Coffee Bean derivatives (stimulants) are used, the most frequently reported side effects are related to its action on the central nervous system and cardiovascular system:
Arabica Coffee Bean products, whether used for diagnostic allergy testing or as a stimulant, must be handled with caution. The primary safety concerns involve cardiovascular stimulation and the potential for severe allergic reactions. Patients with underlying heart conditions, anxiety disorders, or a history of severe allergies must disclose their full medical history to their healthcare provider before exposure.
No FDA black box warnings for Arabica Coffee Bean have been issued. However, the FDA requires all allergenic extracts to carry a general warning regarding the risk of life-threatening allergic reactions. These extracts are not intended for self-administration.
Arabica Coffee Bean products must NEVER be used in the following circumstances:
Conditions requiring a careful risk-benefit analysis by a healthcare provider:
Arabica Coffee Bean derivatives (caffeine) are classified as FDA Pregnancy Category C (under the old system). Data from observational studies suggest that high caffeine intake (over 300 mg per day) may be associated with an increased risk of spontaneous abortion (miscarriage) and intrauterine growth restriction (low birth weight). The American College of Obstetricians and Gynecologists (ACOG) currently recommends that pregnant women limit caffeine consumption to less than 200 mg per day. There is no evidence of teratogenicity (birth defects) at moderate doses, but the substance does cross the placenta and can affect the fetal heart rate.
Caffeine from Arabica Coffee Bean is excreted into breast milk in small amounts (approximately 1% of the maternal plasma level). While generally considered compatible with breastfeeding by the American Academy of Pediatrics (AAP), excessive intake by the mother can lead to irritability, poor sleeping patterns, and 'jitteriness' in the nursing infant. This is especially true for preterm or very young infants who have a reduced ability to metabolize methylxanthines.
Arabica Coffee Bean exerts its effects through several distinct molecular pathways:
Common questions about Kids Relief
Arabica Coffee Bean is primarily used in clinical medicine for two distinct purposes: as an allergenic extract and as a source of caffeine. As an allergenic extract, it is used by specialists to diagnose coffee-related allergies through skin testing or to treat them via immunotherapy. Its most famous component, caffeine, is used therapeutically to treat neonatal apnea (breathing gaps in premature babies), as an adjunct to treat migraines, and to temporarily increase mental alertness. It works by blocking adenosine receptors in the brain, which prevents drowsiness and stimulates the central nervous system. Your doctor may recommend specific preparations based on whether you need diagnostic testing or therapeutic stimulation.
The most common side effects associated with Arabica Coffee Bean derivatives are related to its stimulant properties and include insomnia, nervousness, and a rapid heart rate (tachycardia). Many users also report gastrointestinal issues such as heartburn or nausea because the substance increases stomach acid production. Jitteriness and increased urination (diuresis) are also very frequent, especially in individuals who do not consume coffee regularly. These effects are usually dose-dependent and subside as the substance is metabolized by the liver. If these symptoms become severe or lead to chest pain, you should contact a healthcare provider immediately.
Combining alcohol with Arabica Coffee Bean derivatives is generally discouraged by healthcare professionals. Caffeine is a stimulant that can mask the sedative effects of alcohol, potentially leading you to feel more alert than you actually are, which increases the risk of 'wide-awake drunkenness' and associated accidents. Furthermore, both substances are diuretics, which significantly increases the risk of dehydration and electrolyte imbalance. Some studies also suggest that the combination can put extra strain on the cardiovascular system, leading to higher blood pressure or irregular heartbeats. Always consult your doctor about your specific health risks before mixing these substances.
During pregnancy, Arabica Coffee Bean derivatives should be used with caution and in limited quantities. Most major health organizations, including the American College of Obstetricians and Gynecologists (ACOG), recommend limiting caffeine intake to less than 200 mg per day, which is roughly the amount in one 12-ounce cup of coffee. High intake has been linked in some studies to an increased risk of miscarriage and low birth weight because caffeine readily crosses the placenta to the fetus. Since the fetus cannot metabolize caffeine efficiently, it can lead to prolonged exposure and potential stress on the fetal heart. Always discuss your caffeine consumption with your obstetrician to ensure it is safe for your specific pregnancy.
The onset of action for Arabica Coffee Bean derivatives is quite rapid, with effects typically beginning within 15 to 45 minutes after oral ingestion. Peak levels in the bloodstream are usually reached within 1 to 2 hours. If used as an allergenic extract for skin testing, a reaction (such as a wheal or redness) typically appears within 15 to 20 minutes. The duration of the stimulant effect usually lasts between 3 and 6 hours in a healthy adult, though this can be much longer in people with liver issues or those taking certain medications like birth control. Factors like food intake can slightly delay the start of the effect but do not change the overall impact.
If you have been using high doses of Arabica Coffee Bean derivatives daily, stopping suddenly can lead to 'Caffeine Withdrawal Syndrome.' This condition is medically recognized and typically involves symptoms like severe, throbbing headaches, extreme fatigue, irritability, and difficulty concentrating. These symptoms usually start 12 to 24 hours after the last dose and can last for several days. To avoid this, healthcare providers recommend a gradual taper, reducing your intake by about 25% every few days. This allows your brain's adenosine receptors to return to their normal baseline without causing significant physical distress.
If you miss a therapeutic dose of an Arabica Coffee Bean-based medication, you should take it as soon as you remember. However, if it is already close to the time for your next scheduled dose, it is better to skip the missed dose entirely. Do not take two doses at once to make up for the one you missed, as this can lead to symptoms of overdose such as severe anxiety, heart palpitations, and tremors. If the dose was intended for sleep-related wakefulness and it is late in the day, skipping it may be necessary to prevent insomnia. Always follow the specific guidance provided by your prescribing physician.
Arabica Coffee Bean itself does not cause weight gain and is actually often associated with modest weight loss or weight maintenance. Caffeine is known to slightly increase the metabolic rate (thermogenesis) and can act as a mild appetite suppressant in some individuals. However, many commercial coffee products contain high amounts of added sugars and fats, which can contribute to weight gain if consumed in excess. Additionally, if the stimulant effects lead to poor sleep, this can disrupt hormones like ghrelin and leptin, which regulate hunger, potentially leading to increased calorie intake. From a purely pharmacological standpoint, the active ingredients in the bean are not linked to fat storage.
Arabica Coffee Bean has several significant drug interactions that you must be aware of. It is primarily metabolized by the CYP1A2 enzyme in the liver, so any drug that inhibits this enzyme (like ciprofloxacin or fluvoxamine) can cause caffeine levels to rise dangerously high. It can also interfere with the absorption of certain minerals like calcium and iron, and it may reduce the effectiveness of medications for anxiety or sleep. Conversely, it can dangerously increase the effects of other stimulants or MAO inhibitors. Because of these complex interactions, it is vital to provide your healthcare provider with a complete list of all medications and supplements you are currently taking.
Yes, the active components of Arabica Coffee Bean, specifically caffeine, are widely available in generic forms. Generic caffeine tablets (100 mg or 200 mg) are inexpensive and widely accessible over-the-counter. In the clinical setting, caffeine citrate used for neonatal apnea is also available as a generic injectable or oral solution. Allergenic extracts of Arabica Coffee Bean are produced by various specialized laboratories and are generally referred to by their standard name rather than a brand name. Generic versions are required by the FDA to have the same quality and strength as brand-name versions, though non-standardized extracts may vary slightly between manufacturers.
Other drugs with the same active ingredient (Arabica Coffee Bean)
> Warning: Stop using Arabica Coffee Bean products and call your doctor immediately or seek emergency care if you experience any of the following:
Prolonged use of Arabica Coffee Bean derivatives can lead to several chronic issues:
There are currently no FDA black box warnings specifically for Arabica Coffee Bean allergenic extracts or standardized caffeine tablets. However, clinicians are warned that allergenic extracts carry a risk of severe systemic reactions, including anaphylaxis, and must only be administered by trained personnel in facilities equipped with emergency resuscitation equipment.
Report any unusual symptoms or persistent side effects to your healthcare provider. Monitoring of heart rate and blood pressure is recommended for those using high-dose therapeutic preparations.
For patients using therapeutic doses of Arabica Coffee Bean derivatives:
While Arabica Coffee Bean is intended to increase alertness, it can also cause tremors, dizziness, and 'jitteriness' that may impair fine motor skills. Patients should assess their individual response before driving or operating heavy machinery. If the substance causes significant hand tremors or anxiety, avoid these activities.
Alcohol and Arabica Coffee Bean derivatives have complex interactions. Caffeine can mask the depressant effects of alcohol, leading individuals to feel 'less drunk' than they actually are. This increases the risk of alcohol-related injuries. Furthermore, both substances are diuretics and can lead to significant dehydration.
Do not stop taking high-dose Arabica Coffee Bean derivatives abruptly if you have used them daily for a long period. A gradual tapering (reduction) of the dose is recommended to avoid withdrawal symptoms such as throbbing headaches, extreme lethargy, and irritability. Withdrawal symptoms typically begin 12 to 24 hours after the last dose and can last for up to a week.
> Important: Discuss all your medical conditions, especially heart or psychiatric issues, with your healthcare provider before starting Arabica Coffee Bean products.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking, as the CYP1A2 pathway is highly susceptible to interactions.
Patients allergic to Arabica Coffee Bean may also show cross-sensitivity to:
> Important: Your healthcare provider will evaluate your complete medical history, especially your cardiovascular and allergy profile, before prescribing or administering Arabica Coffee Bean extracts.
Elderly patients (65 years and older) often have a reduced clearance of methylxanthines due to age-related declines in hepatic (liver) function. They are also more likely to have underlying cardiovascular disease or insomnia. Clinical guidelines suggest starting with the lowest possible dose and monitoring for agitation, confusion, and heart palpitations. There is also an increased risk of falls if the substance causes significant tremors or dizziness.
In patients with a Glomerular Filtration Rate (GFR) below 30 mL/min, the metabolites of Arabica Coffee Bean can accumulate. While not typically requiring a dose reduction for occasional use, chronic therapeutic use should be monitored closely for signs of 'methylxanthine-like' toxicity.
This is the most critical population for dose adjustment. In patients with Child-Pugh Class B or C hepatic impairment, the half-life of caffeine can extend from 5 hours to over 50 hours. Therapeutic doses must be reduced by at least 50% to 75% to prevent severe accumulation and toxicity.
> Important: Special populations require individualized medical assessment to ensure the benefits of Arabica Coffee Bean products outweigh the risks.
| Parameter | Value |
|---|---|
| Bioavailability | 99% |
| Protein Binding | 15% - 36% |
| Half-life | 3 - 7 hours (Adults) |
| Tmax | 0.5 - 2 hours |
| Metabolism | Hepatic (CYP1A2) |
| Excretion | Renal (<1% unchanged) |
Arabica Coffee Bean is classified as a Non-Standardized Food Allergenic Extract [EPC]. Its active component, caffeine, is a Methylxanthine [EPC] and a Central Nervous System Stimulant [EPC]. It is related to other methylxanthines such as theophylline (used for asthma) and theobromine (found in chocolate).