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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Butyl Methoxydibenzoylmethane, Ethylhexyl Salicylate, Homosalate, Octocrylene
Brand Name
Skin1004 Madagascar Centella Hyalu-cica Water-fit Sun Serum Uv
Generic Name
Butyl Methoxydibenzoylmethane, Ethylhexyl Salicylate, Homosalate, Octocrylene
Active Ingredient
Butyl MethoxydibenzoylmethaneCategory
Other
Variants
1
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| 2.7 g/100mL | CREAM | TOPICAL | 85796-2805 |
Detailed information about Skin1004 Madagascar Centella Hyalu-cica Water-fit Sun Serum Uv
References used for this content
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Skin1004 Madagascar Centella Hyalu-cica Water-fit Sun Serum Uv, you must consult a qualified healthcare professional.
Butyl Methoxydibenzoylmethane, commonly known as Avobenzone, is a critical organic sunscreen agent belonging to the dibenzoylmethane derivative class, primarily used for broad-spectrum UVA protection.
For Butyl Methoxydibenzoylmethane to provide the labeled level of protection (SPF), it must be applied at a specific density. The standard clinical recommendation is 2 milligrams of product per square centimeter (2 mg/cm²) of skin.
There are currently no specific dosage adjustments required for patients with kidney disease, as systemic absorption is minimal. However, patients with end-stage renal disease (ESRD) who may have 'uremic pruritus' (itchy skin) should use fragrance-free formulations to avoid further irritation.
No dosage adjustments are necessary for patients with liver impairment. While the liver is involved in metabolizing any absorbed fraction, the levels are typically too low to necessitate a change in topical application.
Older adults often have 'atrophic skin' (thinned skin). While no dose reduction is needed, elderly patients should be monitored for signs of irritant contact dermatitis, as their skin barrier may be more easily compromised.
If you forget to apply Butyl Methoxydibenzoylmethane before sun exposure, apply it as soon as you remember. However, be aware that the skin may have already sustained UV damage. If you are already outdoors and realize you missed a dose, seek shade immediately until the product has been applied and had time to set.
> Important: Follow your healthcare provider's dosing instructions and the directions on the OTC 'Drug Facts' label. Do not adjust your application frequency without medical guidance, especially if you have a history of skin cancer.
Butyl Methoxydibenzoylmethane is generally well-tolerated, but because it is a chemical filter, some users may experience localized skin reactions. Common effects include:
> Warning: Stop using products containing Butyl Methoxydibenzoylmethane and call your doctor immediately if you experience any of the following:
There has been ongoing scientific debate regarding the long-term effects of systemic absorption of Butyl Methoxydibenzoylmethane.
There are currently no FDA Black Box Warnings for Butyl Methoxydibenzoylmethane. It is categorized as GRASE (Generally Recognized As Safe and Effective) for its intended use as a topical sunscreen agent.
Report any unusual symptoms, persistent rashes, or severe skin changes to your healthcare provider. If you suspect a photoallergy, a dermatologist can perform 'photopatch testing' to confirm the diagnosis.
Butyl Methoxydibenzoylmethane is for external use only. It is not meant to be ingested or applied to mucosal membranes (inside the mouth, nose, or genitals). While it is highly effective at blocking UVA rays, it does not provide 100% protection. Users should always combine sunscreen use with other protective measures, such as wearing hats, sunglasses, and seeking shade during peak UV hours (10 AM to 4 PM).
No FDA black box warnings for Butyl Methoxydibenzoylmethane. It has a long history of safe use in the global consumer market.
There are no routine lab tests (like blood counts or liver panels) required for the standard use of Butyl Methoxydibenzoylmethane. However, patients using it for medical reasons (e.g., preventing flares of Lupus) should have regular skin examinations by a dermatologist to monitor for:
Butyl Methoxydibenzoylmethane does not cause drowsiness or cognitive impairment. It has no known effect on the ability to drive or operate heavy machinery.
There is no known interaction between the topical use of Butyl Methoxydibenzoylmethane and the consumption of alcohol. However, alcohol consumption can cause vasodilation (widening of blood vessels), which may make the skin feel warmer or more sensitive to the 'stinging' sensation sometimes associated with sunscreens.
If you develop a persistent rash, swelling, or itching, you should discontinue use immediately. There is no 'withdrawal' syndrome associated with stopping Butyl Methoxydibenzoylmethane. However, stopping use will immediately leave your skin vulnerable to UVA radiation, so an alternative protection method (like a physical blocker or UV-protective clothing) must be substituted.
> Important: Discuss all your medical conditions, especially history of skin cancer or eczema, with your healthcare provider before starting a new regimen containing Butyl Methoxydibenzoylmethane.
There are no absolute drug-drug contraindications for topical Butyl Methoxydibenzoylmethane. However, certain chemical combinations in the same bottle are avoided by manufacturers:
There are no known food interactions with topically applied Butyl Methoxydibenzoylmethane. It does not interact with grapefruit, dairy, or caffeine.
For each interaction, the management strategy is typically 'staggered application'—leaving time between the application of different topical products.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking, even if they are 'natural' or over-the-counter.
Butyl Methoxydibenzoylmethane must NEVER be used in the following circumstances:
Conditions requiring careful risk-benefit analysis by a physician:
There is a potential for cross-sensitivity between Butyl Methoxydibenzoylmethane and certain fragrances or chemical preservatives. Specifically, individuals allergic to Isolates of Balsam of Peru or certain dibenzoylmethane-based dyes may also react to this sunscreen agent.
> Important: Your healthcare provider will evaluate your complete medical history and skin type before recommending a specific sunscreen formulation.
FDA Pregnancy Category: Not formally assigned (as it is an OTC topical), but generally considered safe for use during pregnancy.
No dosage adjustment is required for patients with renal impairment. The amount absorbed systemically is negligible compared to the body's clearance capacity, even in those with reduced GFR (Glomerular Filtration Rate).
No dosage adjustment is required. Even in patients with Child-Pugh Class C cirrhosis, the topical application of Butyl Methoxydibenzoylmethane does not pose a known risk of hepatotoxicity.
> Important: Special populations, particularly pregnant women and those with chronic skin conditions, require individualized medical assessment to choose the safest photoprotection strategy.
Butyl Methoxydibenzoylmethane is a UVA filter. Its molecular structure contains a conjugated system that allows it to absorb high-energy UV photons. Specifically, it targets the 320–400 nm range. When it absorbs light, it undergoes an intramolecular hydrogen transfer, moving from an 'enol' tautomer to a 'keto' tautomer. This process dissipates the energy as heat. Because it covers the UVA-I range (340–400 nm), it is one of the few organic molecules capable of protecting against the wavelengths that penetrate most deeply into the skin and cause long-term structural damage.
| Parameter | Value |
|---|---|
| Bioavailability | <1-2% (Topical) |
| Protein Binding | Not definitively characterized in humans |
| Half-life | 33–55 hours (Systemic fraction) |
| Tmax | 24 hours (Time to peak plasma level after repeated application) |
| Metabolism | Likely Hepatic (Glucuronidation) |
| Excretion | Primarily Renal |
Butyl Methoxydibenzoylmethane is classified as an Organic UVA Filter. It is often grouped with other chemical sunscreens like Oxybenzone and Octisalate, though its specific UVA-I coverage distinguishes it from most other members of the class.
Common questions about Skin1004 Madagascar Centella Hyalu-cica Water-fit Sun Serum Uv
Butyl Methoxydibenzoylmethane, also known as Avobenzone, is primarily used as an active ingredient in sunscreens to provide broad-spectrum protection against Ultraviolet A (UVA) rays. These rays are responsible for premature skin aging, wrinkles, and long-term DNA damage that can lead to skin cancer. Unlike many other sunscreen ingredients that only block UVB rays (which cause sunburn), this compound is one of the few that covers the entire UVA spectrum. It is found in daily moisturizers, sunscreens, and cosmetics to help prevent photoaging and reduce the risk of skin malignancies. Healthcare providers often recommend products containing this ingredient for patients with light-sensitive conditions like lupus.
The most common side effects are localized skin reactions, such as mild stinging, burning, or itching immediately after application. Some users may develop a red rash known as contact dermatitis, which is often a reaction to the cream base or other additives in the sunscreen. If the product gets into the eyes, it can cause significant irritation and tearing. In rare cases, some individuals may experience a 'photoallergy,' where a rash only appears after the skin with the sunscreen is exposed to sunlight. Most side effects are minor and resolve quickly once the product is washed off the skin.
Yes, there is no known interaction between the topical application of Butyl Methoxydibenzoylmethane and the consumption of alcohol. Because the ingredient is applied to the skin and very little enters the bloodstream, it does not interfere with how the body processes alcohol. However, alcohol can cause the skin's blood vessels to dilate, which might make your skin feel more sensitive or prone to redness when applying topical products. Additionally, excessive alcohol consumption can lead to dehydration, which may worsen the skin dryness sometimes caused by alcohol-based sunscreen sprays. Always use caution when applying flammable sunscreen sprays near someone who is smoking or near an open flame.
Butyl Methoxydibenzoylmethane is generally considered safe for use during pregnancy, and most dermatologists recommend its use to prevent melasma (dark skin patches) which often occurs due to hormonal changes. While recent studies have shown that small amounts of the chemical can be absorbed into the bloodstream, there is currently no evidence that this poses a risk to the developing fetus. The American College of Obstetricians and Gynecologists emphasizes the importance of sun protection during pregnancy to prevent skin damage. If you have concerns about chemical absorption, you can discuss using 'physical' or 'mineral' sunscreens containing zinc oxide with your doctor. Always consult your healthcare provider before starting new skincare routines during pregnancy.
Butyl Methoxydibenzoylmethane begins to work as soon as it is applied to the skin, but it requires about 15 to 20 minutes to form a stable, protective film. This 'setting' time is crucial because it ensures the product has bonded with the outer layer of the skin and won't be easily wiped or sweated off. If you go directly into intense sunlight or water immediately after application, the protection may be uneven or significantly reduced. For the best results, healthcare providers recommend applying the product indoors before you head outside. This allows the active ingredients to provide the full Sun Protection Factor (SPF) and UVA protection labeled on the bottle.
Yes, you can stop using products containing Butyl Methoxydibenzoylmethane at any time without experiencing withdrawal symptoms or physical side effects. Since it is a topical agent and not a systemic medication, your body does not become dependent on it. However, the moment you stop applying it, your skin loses its protection against harmful UVA radiation. If you have been using it to manage a medical condition like photosensitivity or to prevent skin cancer, you should immediately substitute it with another form of protection, such as a different sunscreen or UV-protective clothing. Consult your dermatologist if you are stopping use due to a suspected allergic reaction.
If you forget to apply Butyl Methoxydibenzoylmethane before going into the sun, apply it as soon as you realize the omission. While the skin may have already received some UV damage, applying it late is still better than not applying it at all for the remainder of your time outdoors. If you are already in the sun, try to find shade for 15 minutes after the late application to allow the film to set properly. Remember that sun damage is cumulative, so missing doses frequently can increase your long-term risk of skin aging and cancer. It is helpful to keep a travel-sized bottle in your bag or car to avoid missing applications when away from home.
No, Butyl Methoxydibenzoylmethane does not cause weight gain. It is a topical sunscreen ingredient that stays primarily on the surface of the skin, and the tiny amount that may be absorbed into the bloodstream is not enough to affect your metabolism, appetite, or fat storage. Unlike certain systemic medications like steroids or some antidepressants, topical UV filters have no mechanism for altering body weight. Any changes in weight you experience while using sunscreens are likely due to other factors such as diet, exercise, or unrelated medical conditions. If you have concerns about unexpected weight changes, you should discuss them with your primary care physician.
Butyl Methoxydibenzoylmethane is generally safe to use alongside most oral medications. However, it can interact with other topical products applied to the same area of skin. For example, using it with insect repellents containing DEET can reduce the effectiveness of the sunscreen. It is also important to be cautious if you are using topical acne treatments like benzoyl peroxide or retinoids, as these can make your skin more sensitive to irritation from the sunscreen. To avoid issues, it is usually recommended to apply medicated creams first, wait for them to absorb fully, and then apply the sunscreen. Always inform your doctor about all topical and oral treatments you are using.
Butyl Methoxydibenzoylmethane is the 'generic' or chemical name for the ingredient often marketed under the trade name Avobenzone. It is not a prescription drug, so it doesn't have a 'generic version' in the traditional sense of a pill. Instead, it is an active ingredient found in hundreds of different over-the-counter sunscreen brands, ranging from expensive luxury products to affordable store-brand versions. Regardless of the brand name or price, the FDA regulates the concentration of Butyl Methoxydibenzoylmethane to ensure it is safe and effective. You can check the 'Active Ingredients' section of the Drug Facts label on any sunscreen bottle to see if it contains this specific compound.
Other drugs with the same active ingredient (Butyl Methoxydibenzoylmethane)